This book provides a comprehensive overview of percutaneous nephrolithotomy, covering topics including its history, anatomy, preoperative preparation, clinical operation, and postoperative treatment. It presents both basic and advanced techniques, such as micro-PNL, mini-PNL, ultra-mini-PNL, and super mini-PNL, together with representative clinical cases. In addition, the book describes potential technical issues, complications, indications and contraindications in detail, making it a valuable reference guide for urologists, especially those who wish to improve their PCNL skills in clinical practice.