Gabimaru is a ninja on death row with one chance to see his wife again--by finding the elixir of immortality on a supernatural island and delivering it to the shogun. Standing in his way are his fellow convicts and the fearsome beasts that roam the island, devouring or killing anyone they encounter.

A group of samurai and ninja arrive on the cursed island with exactly one mission--to leave no one alive. Any who would stand in opposition to the Yamada Asaemon, and therefore the shogun, must die. Any who do not fear the power of the ninja village Iwagakure must die. Gabimaru, Sagiri and the others have overcome a great deal, but this will be a struggle like they've never experienced before.