FBI Agents Terry Longfellow and Adriana Dickinson are called on to investigate a case that became known as the Decapitator at FBI headquarters. The agents track the serial killer from Jamestown, New York, to Philadelphia, Pennsylvania, to Moundsville, West Virginia, to Pittsburgh, Pennsylvania, and to Western Maryland, which becomes his killing field. The Decapitator leaves countless clues for Agents Longfellow and Dickinson, challenging them with his arrogance in a game of cat and mouse.