The era of therapeutic nihilism in dementia has ended, with the emergence of agents for symptomatic treatment, those that delay the course of the disease or prevent the onset of dementia, and new methods to manage symptoms. This work collects information on new therapies, distills what is relevant and reliable, and presents it in a format that is useful to clinicians who manage and treat people with dementia. It brings together evidence on all aspects of the disease and its management, from diagnosis and therapy to social and ethical considerations.