1. Introduction.- 2. Foundations.- Part I: Challenges and Concepts.- 3. Overview of Challenges in Composing Model-Based Analysis Tools.- 4. Composition of Languages,Models, and Analyses.- 5. Integration and Orchestration of Analysis Tools.- 6. Continual Model-Based Analysis.- 7. Exploiting Results of Model-Based Analysis Tools.- 8. Living with Uncertainty in Model-Based Development.- Part II: Case Studies.- GTSMorpher: Safely Composing Behavioural Analyses Using Structured Operational Semantics.- 10. Compositional Modelling Languages with Analytics and Construction Infrastructures Based on Object-Oriented Techniques-The MontiCore Approach.- 11. Challenges in the Evolution of Palladio-Refactoring Design Smells in a Historically-Grown Approach to Software Architecture Analysis.- 12. AnATLyzer: Static Analysis of ATL Model Transformations.- 13. Using Afra in Different Domains by Tool Orchestration.- 14. Conclusion.